Interpretation of very low resolution X-ray electron-density maps using core objects.
Interpretation of very low resolution X-ray electron-density maps using core objects.
复制标题
使用核心物体解释极低分辨率 X 射线电子密度图。
DOI：
10.1107/s090744490901991x
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
Lamzin,VictorS
中科院分区：
文献类型：
--
作者：
Heuser,Philipp;Langer,GerritG;Lamzin,VictorS
A novel approach to obtaining structural information from macromolecular X-ray data extending to resolutions as low as 20 Å is presented. Following a simple map-segmentation procedure, the approximate shapes of the domains forming the structure are identified. A pattern-recognition comparative analysis of these shapes and those derived from the structures of domains from the PDB results in candidate structural models that can be used for a fit into the density map. It is shown that the placed candidate models can be employed for subsequent phase extension to higher resolution.
