Adhesion of red cells to foreign surfaces in the presence of flow.
Adhesion of red cells to foreign surfaces in the presence of flow.
复制标题
在存在流动的情况下红细胞粘附到异物表面。
DOI：
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发表时间：
1974
期刊：
影响因子：
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通讯作者：
E. E. Spaeth
中科院分区：
文献类型：
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作者：
N. Mohandas;R. Hochmuth;E. E. Spaeth
在旋转圆盘或平行板流动系统中由层流产生的受控表面剪切应力已被用于研究红细胞对玻璃、硅化玻璃、聚乙烯和聚四氟乙烯的粘附。结果表明，细胞表面的剪切应力必须超过一个最小临界值，细胞才能脱离，而且这个最小临界剪切应力随着细胞表面接触时间的增加而增加。结果还表明，从清洁表面分离的最小临界剪切应力与所研究的四种材料的材料的临界表面张力相关。对蛋白质涂层表面的研究表明，白蛋白会导致粘附强度适度降低。的效果的大小被认为是显着的影响，由基层材料。
A controlled surface shear stress produced by laminar flow in a rotating disk or parallel plate flow system has been used to study red cell adhesion to glass, siliconized glass, polythylene and Teflon. The results indicate that the shear stress at the surface must exceed a minimum critical value before cells will detach, and that this minimum critical shear stress increases as the time of cellsurface contact is increased. The results also indicate that the minimum critical shear stress for detachment from clean surfaces correlates with the critical surface tension of the material for the four materials studied. Studies with proteincoated surfaces indicate that albumin causes a moderate reduction in the strength of adhesion. The magnitude of the effect was found to be influenced significantly by the substratum material.