Bond breaking and temporary anion states in uracil and halouracils: implications for the DNA bases.
Bond breaking and temporary anion states in uracil and halouracils: implications for the DNA bases.
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尿嘧啶和盐尿嘧啶中的键断裂和临时阴离子状态：对 DNA 碱基的影响。
DOI：
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发表时间：
2004
影响因子：
8.6
通讯作者：
P. Burrow
中科院分区：
文献类型：
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作者：
A. Scheer;K. Aflatooni;G. Gallup;P. Burrow
低能电子能够通过解离电子附着过程破坏气相DNA碱基中的键。借助于新的全散射数据和量子化学计算的输入，我们描述了这些化合物中的偶极束缚态和价阴离子态，并给出了出现在横截面上的两种结构的分配。明确区分这两种键断裂机制对于理解电子诱导的DNA损伤是必要的。
Low energy electrons are capable of breaking bonds in gas phase DNA bases by means of the dissociative electron attachment process. With the aid of new total scattering data in the halouracils and input from quantum chemical calculations, we describe the dipole bound and valence anion states in these compounds and present assignments for the two types of structure appearing in the cross sections. A clear distinction between the two mechanisms for bond breaking is necessary for an understanding of electron induced damage to DNA.