Serum sodium ion level influenced by daily salt intake after administration of sodium-glucose cotransporter 2 inhibitors.

Serum sodium ion level influenced by daily salt intake after administration of sodium-glucose cotransporter 2 inhibitors.
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施用钠-葡萄糖协同转运蛋白 2 抑制剂后,血清钠离子水平受每日盐摄入量的影响。

DOI:
10.1016/j.nut.2017.05.008
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发表时间:
2018
期刊:
Nutrition.
影响因子:
--
通讯作者:
Yamada M.
Yamada M.
中科院分区:
--
文献类型:
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作者:
Yamada E;Osaki A;Saito T;Niijima Y;Okada J;Okada S;Yamada M.

文献摘要

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To investigate this, we conducted a clinical study that included 20 patients with T2DM (11 men and 9 women; median age, 69 y), who visited Kan-etsu Chuo Hospital once a month for a regular follow-up examination during which glucose concentrations in plasma, serum sodium, and glycated hemoglobin (HbA1c) levels were assessed. The patients had the following characteristics and mean data: body mass index, 26.3 kg/m2; systolic blood pressure, 130 mm Hg; diastolic blood pressure, 77.3 mm Hg; total cholesterol, 220.5 mg/dL; triacylglycerol, 135 mg/dL; and uric acid, 6.1 mg/dL.[...] analysis with a larger number of patients is required to confirm the present results. 1 L. Chen, LM LaRocque, O. Efe, J. Wang, JM Sands, JD Klein, Effect of dapagliflozin treatment on fluid and electrolyte balance in diabetic rats, Am J Med Sci, Vol. 352, 2016, 517-523 2 T. Ito, M. Takeda, T. Hamano, T. Kijima, M. Yamasaki, M. Isomura, Effect of salt intake on blood pressure in patients receiving antihypertensive therapy: