Nfkbid-mediated humoral immunity during secondary toxoplasmosis.
Nfkbid-mediated humoral immunity during secondary toxoplasmosis.
复制标题
继发性弓形体病期间 Nfkbid 介导的体液免疫。
DOI：
10.1016/j.pt.2022.01.010
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发表时间：
2022
影响因子：
9.6
通讯作者：
Moretto,Magali
中科院分区：
文献类型：
--
作者：
Khan,ImtiazA;Moretto,Magali
疫苗介导的寄生虫免疫尚未实现。免疫C57 BL/6小鼠易继发弓形虫感染。Souza等人使用正向遗传学方法，鉴定Nfkbid为在二次弓形虫感染期间调节B细胞免疫和保护免于再攻击的重要因子。
Vaccine-mediated immunity to parasites has not been achieved. Immune C57BL/6 mice are susceptible to secondaryToxoplasma gondiiinfection. Using a forward genetics approach, Souza et al. identify Nfkbid as an important factor for the regulation of B cell immunity during secondaryToxoplasmainfection and protection against rechallenge.