Prevalence of dementia in Latin America: a collaborative study of population-based cohorts.
Prevalence of dementia in Latin America: a collaborative study of population-based cohorts.
复制标题
DOI：
10.1017/s1041610209009430
复制
发表时间：
2009-08
影响因子：
7
通讯作者：
Caramelli P
中科院分区：
文献类型：
--
作者：
Nitrini R;Bottino CM;Albala C;Custodio Capuñay NS;Ketzoian C;Llibre Rodriguez JJ;Maestre GE;Ramos-Cerqueira AT;Caramelli P
痴呆症正在成为拉丁美洲（LA）的一个主要公共卫生问题，但该地区有关痴呆症的流行病学信息仍然很少。本研究分析了洛杉矶痴呆症患病率的流行病学研究数据，并比较了洛杉矶各国痴呆症的患病率及其原因，并试图澄清与世界发达地区的差异。对LA痴呆率的人群研究进行了数据库检索。检索中还纳入了摘要。出版物的作者被邀请参加这项合作研究，与小组分享缺失或更新的数据分析。纳入了来自6个国家的8项研究。老年人（≥65岁）痴呆的全球患病率为7.1%（95% CI：6.8-7.4），与发达国家的患病率一致。然而，在LA研究中，相对年轻的受试者（65-69岁）的患病率较高。老年人的文盲率为9.3%，文盲中痴呆的患病率是识字者的两倍。阿尔茨海默病是痴呆症最常见的原因。与来自发达国家的研究相比，LA的痴呆症的全球患病率被证明是相似的，尽管在相对年轻的受试者中痴呆症的患病率更高，这可能与低教育水平和较低的认知储备之间的关联有关，导致LA老年人群中痴呆症的临床体征更早出现。
Dementia is becoming a major public health problem in Latin America (LA), yet epidemiological information on dementia remains scarce in this region. This study analyzes data from epidemiological studies on the prevalence of dementia in LA and compares the prevalence of dementia and its causes across countries in LA and attempts to clarify differences from those of developed regions of the world. A database search for population studies on rates of dementia in LA was performed. Abstracts were also included in the search. Authors of the publications were invited to participate in this collaborative study by sharing missing or more recent data analysis with the group. Eight studies from six countries were included. The global prevalence of dementia in the elderly (≥65 years) was 7.1% (95% CI: 6.8–7.4), mirroring the rates of developed countries. However, prevalence in relatively young subjects (65–69 years) was higher in LA studies The rate of illiteracy among the elderly was 9.3% and the prevalence of dementia in illiterates was two times higher than in literates. Alzheimer’s disease was the most common cause of dementia. Compared with studies from developed countries, the global prevalence of dementia in LA proved similar, although a higher prevalence of dementia in relatively young subjects was evidenced, which may be related to the association between low educational level and lower cognitive reserve, causing earlier emergence of clinical signs of dementia in the LA elderly population.