Evaluation of a model-based attenuation correction method on whole-body 18F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging
Evaluation of a model-based attenuation correction method on whole-body 18F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging
复制标题
基于模型的全身 18F-氟脱氧葡萄糖正电子发射断层扫描/磁共振成像衰减校正方法的评估
DOI：
10.1007/s12194-020-00605-z
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发表时间：
2021
影响因子：
1.6
通讯作者：
Ito Hiroshi
中科院分区：
文献类型：
--
作者：
Kubo Hitoshi;Nemoto Ayaka;Ukon Naoyuki;Ito Hiroshi
不能使用Dixon序列的磁共振衰减校正(MRAC)来评估骨骼。为了解决这一问题，本研究旨在通过创建骨分割来评估基于模型的AC在全身2-[氟-18]-氟-2-脱氧-d-葡萄糖(18F-FDG)正电子发射断层扫描(PET)/磁共振成像(MRI)中的应用。我们对连续31例患者的数据进行了分析和评估。采用Bioggraph MMR(西门子医疗设备)进行临床全身18F-FDG PET/MRI常规MRAC扫描，用OSIRIX MD软件进行图像分析。检查结束后，应用新的基于模型的后处理MRAC生成带骨分割的μ图，并使用该μ图进行回顾性正电子发射计算机断层扫描重建。使用基于模型的MRAC创建的所有患者的骨结构都被直观地评估。测量并比较正电子发射计算机断层扫描图像中11个解剖位置的标准摄取值(SUV)，这些标准摄取值使用μ-MAP进行了校正，并进行了骨分割和不分割。对所有患者运行基于模型的后处理MRAC，没有错误。目测评估显示，基于模型的后处理MRAC对6名患者显示较差的结果。此外，与常规方法相比，大脑中的SUV呈现出增加的趋势。大脑以外的其他部位也显示出类似或减少的趋势。两种方法对所有患者均有良好的线性相关性。然而，20岁的 患者与20岁的≥ 患者表现出不同的趋势。在对年轻患者应用这种基于模型的MRAC时，我们应该谨慎行事。
The bone cannot be evaluated using magnetic resonance attenuation correction (MRAC) with the Dixon sequence. To solve this issue, the present study aimed to evaluate model-based AC for whole-body 2-[fluorine-18]-fluoro-2-deoxy-d-glucose (18F-FDG) positron emission tomography (PET)/magnetic resonance imaging (MRI) by creating bone segmentation. We analyzed and evaluated the data of 31 consecutive patients. The Biograph mMR (Siemens Healthcare) was used for clinical whole-body18F-FDG PET/MRI with the conventional MRAC method, and OSIRIX MD software was used to analyze the images. After the examination, the new model-based post-processing MRAC was applied to create μ-maps with bone segmentation, and retrospective PET reconstruction was performed using this μ-map. The bone structures of all patients created using model-based MRAC were visually evaluated. Standard uptake values (SUVs) at 11 anatomical positions in PET images, corrected using the μ-map with and without bone segmentation, were measured and compared. The model-based post-processing MRAC was run for all patients, without errors. Visual evaluation revealed that the model-based post-processing MRAC exhibited poor results for six patients. Furthermore, it exhibited an increasing trend of SUV in the brain compared to the conventional method. Locations other than the brain indicated a similar or decreasing trend. The two methods showed a good linear correlation for all patients. However, patients aged < 20 years exhibited a different trend from those aged ≥ 20 years. We should exercise caution when applying this model-based MRAC for younger patients.
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正电子发射断层扫描成像在癌症患者评估中的应用。
影响因子：
1
作者：
R. Kumar;P. Bhargava;M. Bozkurt;H. Zhuang;S. Potenta;A. Alavi
通讯作者：
A. Alavi
DOI：
10.1007/s00259-010-1603-1
发表时间：
2011-01-01
影响因子：
9.1
作者：
Schulz, V.;Torres-Espallardo, I.;Krombach, G. A.
通讯作者：
Krombach, G. A.
影响因子：
9.3
作者：
Mehranian, Abolfazl;Zaidi, Habib
通讯作者：
Zaidi, Habib
影响因子：
2.8
作者：
Shandiz MS;Rad HS;Ghafarian P;Yaghoubi K;Ay MR
通讯作者：
Ay MR