Studies on the manganese-mediated isomerization of alkynyl carbonyls to allenyl carbonyls
Studies on the manganese-mediated isomerization of alkynyl carbonyls to allenyl carbonyls
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DOI：
10.1021/jo051040u
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发表时间：
2005-09-02
影响因子：
3.6
通讯作者：
Silvestri, MA
中科院分区：
文献类型：
--
作者：
Lepore, SD;Khoram, A;Silvestri, MA
描述了碱在锰配位的共轭炔基羰基异构化为相应的联烯基羰基中的作用的研究。膦添加剂的使用表明锰在与胺碱异构化之前需要配体。还检查了一系列胺碱在该异构化反应中的功效，揭示了对 pK(a) 的强烈依赖性。相比之下，叔丁醇钾在不添加锰配体的情况下会导致快速异构化。
A study of the role of base in the isomerization of manganese-coordinated conjugated alkynyl carbonyls to the corresponding allenyl carbonyls is described. The use of phosphine additives indicates that manganese requires a ligand prior to isomerization with amine bases. A series of amine bases were also examined for their efficacy in this isomerization reaction revealing a strong dependence on pK(a). By contrast, potassium tert-butoxide led to rapid isomerization in the absence of added manganese ligand.