Enzymatic ligation creates discrete multinanoparticle building blocks for self-assembly
Enzymatic ligation creates discrete multinanoparticle building blocks for self-assembly
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DOI:
10.1021/ja8026746
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发表时间:
2008-07-23
影响因子:
15
通讯作者:
Alivisatos, A. Paul
中科院分区:
文献类型:
--
作者:
Claridge, Shelley A.;Mastroianni, Alexander J.;Alivisatos, A. Paul
Enzymatic ligation of discrete nanoparticle-DNA conjugates creates nanoparticle dimer and trimer structures in which the nanoparticles are linked by single-stranded DNA, rather than by double-stranded DNA as in previous experiments. Ligation was verified by agarose gel and small-angle X-ray scattering. This capability was utilized in two ways: first, to create a new class of multiparticle building blocks for nanoscale self-assembly and, second, to develop a system that can amplify a population of discrete nanoparticle assemblies.