Effects of concurrent access to a single concentration or multiple concentrations of ethanol on ethanol intake by periadolescent high-alcohol-drinking rats

Effects of concurrent access to a single concentration or multiple concentrations of ethanol on ethanol intake by periadolescent high-alcohol-drinking rats
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DOI:
10.1016/s0741-8329(04)00096-5
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发表时间:
2004-06-01
期刊:
影响因子:
2.3
通讯作者:
McBride, WJ
McBride, WJ
中科院分区:
医学4区
文献类型:
--
作者:
Bell, RL;Rodd, ZA;McBride, WJ

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本研究的目的是评估获得不同浓度的乙醇和动物性别对青春期[出生后30 - 60天(PND)]高度饮酒(HAD-1和HAD-2)大鼠乙醇消耗量的影响。在青春期开始时(PND 30),大鼠同时接受单一浓度[15%体积/体积(vol./卷)]或多种浓度[10%、20%和30%(体积/体积)]。卷)]乙醇和水。乙醇消费量数据分析显示,
The objectives of the current study were to assess the effects of access to different concentrations of ethanol and sex of the animal on ethanol consumption of high-alcohol-drinking (HAD-1 and HAD-2) rats during adolescence [postnatal days (PNDs) 30 through 60]. At the beginning of adolescence (PND 30), the rats were given concurrent access to either a single concentration [15% volume/volume (vol./ vol.)] or multiple concentrations [10%, 20%, and 30% (vol./vol.)] of ethanol and water. Analyses of ethanol consumption data revealed significant (P