Hold the salt: vasopressor role for BDNF.
Hold the salt: vasopressor role for BDNF.
复制标题
持盐：对于BDNF有升血管作用。
DOI：
10.1016/j.cmet.2015.03.015
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发表时间：
2015
期刊：
影响因子：
29
通讯作者：
Mattson,MarkP
中科院分区：
文献类型：
--
作者：
Marosi,Krisztina;Mattson,MarkP
在Neuron，Choe et al.（2015）证明脑源性神经营养因子（BDNF）信号通过增加下丘脑加压素分泌神经元的兴奋性介导盐诱导的血压升高。这些发现表明BDNF在适应性心血管反应生理挑战和高血压的发病机制中的复杂作用。
In a recent publication inNeuron, Choe et al. (2015) demonstrate that brain-derived neurotrophic factor (BDNF) signaling mediates salt-induced blood pressure elevation by increasing the excitability of hypothalamic vasopressin-secreting neurons. These findings suggest complex roles for BDNF in adaptive cardiovascular responses to physiological challenges and in the pathogenesis of hypertension.