A Randomized Prospective Study of Bowel Preparation for Colonoscopy with Low-Dose Sodium Phosphate Tablets versus Polyethylene Glycol Electrolyte Solution.
A Randomized Prospective Study of Bowel Preparation for Colonoscopy with Low-Dose Sodium Phosphate Tablets versus Polyethylene Glycol Electrolyte Solution.
复制标题
DOI：
10.1155/2014/879749
复制
发表时间：
2014
影响因子：
2
通讯作者：
Watanabe S
中科院分区：
文献类型：
--
作者：
Kumagai E;Shibuya T;Makino M;Murakami T;Takashima S;Ritsuno H;Ueyama H;Kodani T;Sasaki H;Matsumoto K;Sakamoto N;Osada T;Nagahara A;Ogihara T;Watanabe S
最佳的肠道准备对于结肠镜检查的安全性和结果至关重要。含有聚乙二醇（PEG）的溶液通常用作肠道清洁剂，但有些患者对PEG不耐受，这可能导致结肠镜检查中断。磷酸钠（NaP）片剂旨在提高患者的接受度和依从性。本研究的目的是比较30 NaP片剂制剂（L-NaP）和2 L PEG制剂的肠道准备效率和患者接受度。患者随机分为L-NaP组或PEG组。主要终点是结肠清洁的效率，由内镜医师根据Aronchick量表采用经验证的四点量表进行评估，并由设盲研究者进行验证。次要终点是患者的耐受性和接受度。两种制剂的结肠清洁效率无显著差异。然而，患者的总体判断明显有利于L-NaP，反映了L-NaP比PEG更好的接受性。此外，在假设的未来需要结肠镜检查的情况下，更多的患者倾向于L-NaP而不是PEG。
Optimal bowel preparation is essential for the safety and outcome of colonoscopy. A solution containing polyethylene glycol (PEG) is often used as a bowel cleansing agent, but some patients are intolerant of PEG, and this may lead to discontinuation of colonoscopy. Sodium phosphates (NaP) tablets are designed to improve patient acceptance and compliance. The objective of this study was to compare bowel preparation efficiency and patient acceptance of a 30 NaP tablet preparation (L-NaP) and a 2 L PEG preparation. Patients were randomized into either the L-NaP or PEG group. The primary endpoint was the efficiency of colon cleansing as assessed by a validated four-point scale according to the Aronchick scale by endoscopists and was verified by blinded investigators. The secondary endpoints were patients' tolerability and acceptance. Colon-cleansing efficiency was not significantly different between the two preparations. However, patients' overall judgment was significantly in favor of L-NaP, reflecting better acceptance of L-NaP than PEG. Additionally, more patients favored L-NaP over PEG in a hypothetical future occasion requiring colonoscopy.
登录
查看更多内容
影响因子：
2.4
作者：
Matsuda, Ayako;Matsuda, Tomohiro;Nishimoto, Hiroshi
通讯作者：
Nishimoto, Hiroshi
影响因子：
3.9
作者：
GOLUB, RW;KERNER, BA;AGUILAR, PS
通讯作者：
AGUILAR, PS
影响因子：
3.1
作者：
Gurudu, Suryakanth R.;Li, Feng;Leighton, Jonathan A.
通讯作者：
Leighton, Jonathan A.
影响因子：
4.3
作者：
Tajika, Masahiro;Niwa, Yasumasa;Yamao, Kenji
通讯作者：
Yamao, Kenji
影响因子：
2.9
作者：
Peixoto, AJ;Lassman, MN
通讯作者：
Lassman, MN