Characteristics of infants with severe retinopathy of prematurity in countries with low, moderate, and high levels of development: Implications for screening programs
Characteristics of infants with severe retinopathy of prematurity in countries with low, moderate, and high levels of development: Implications for screening programs
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DOI：
10.1542/peds.2004-1180
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发表时间：
2005-05-01
期刊：
影响因子：
8
通讯作者：
Zin, A
中科院分区：
文献类型：
--
作者：
Gilbert, C;Fielder, A;Zin, A
Objective.早产儿视网膜病变（ROP）是一种潜在的可避免的儿童失明原因。由于ROP导致的失明比例在各国之间差异很大，这取决于其发展水平，受到新生儿护理的可用性，新生儿结局以及有效的筛查和治疗计划是否到位的影响。本研究的目的是比较1996年至2002年在高度发达国家和欠发达国家发生严重ROP的早产儿的特征。这是一项观察性研究。由筛查ROP的低、中、高发育等级国家（3个高度发达国家和10个欠发达国家）的眼科医生完成问卷调查，提供接受阈值ROP治疗或确定为疾病晚期的婴儿的出生体重和胎龄（GA）。对重度ROP患儿的出生体重和GAs进行测量。高度发达国家婴儿的平均出生体重在737至763克之间，而欠发达国家则在903至1 527克之间。高度发达国家婴儿的平均GAs为25.3至25.6周，而欠发达国家为26.3至33.5周。来自不发达国家的1091名婴儿中，共有13.0%超过了英国的筛查标准; 3.6%超过了
Objective. Retinopathy of prematurity (ROP) is a potentially avoidable cause of blindness in children. The proportion of blindness as a result of ROP varies greatly among countries depending on their level of development, being influenced by the availability of neonatal care, neonatal outcomes, and whether effective screening and treatment programs are in place. The objective of this study was to compare characteristics of premature infants who developed severe ROP between 1996 and 2002 in highly developed countries with less developed countries.Methods. This was an observational study. A questionnaire was completed by ophthalmologists in countries with low, moderate, and high development rankings ( 3 highly developed countries and from 10 less well-developed countries) who screen for ROP in which they supplied birth weights and gestational ages (GAs) of infants who were treated for threshold ROP or identified with more advanced stages of the disease. Birth weights and GAs of infants with severe ROP were measured.Results. The mean birth weights of infants from highly developed countries ranged from 737 to 763 g compared with values ranging from 903 to 1527 g in less developed countries. Mean GAs of infants from highly developed countries ranged from 25.3 to 25.6 weeks compared with 26.3 to 33.5 weeks in less developed countries. A total of 13.0% of 1091 infants from poorly developed countries exceeded United Kingdom screening criteria; 3.6% exceeded a criteria of