Plasma growth hormone, insulin-like growth factor I, and insulin-like growth factor binding proteins in pigs with divergent genetic merit for postweaning average daily gain.
Plasma growth hormone, insulin-like growth factor I, and insulin-like growth factor binding proteins in pigs with divergent genetic merit for postweaning average daily gain.
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DOI：
10.2527/1995.7361776x
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发表时间：
1995-06
影响因子：
3.3
通讯作者：
A. Clutter;L. Spicer;M. Woltmann;R. Grimes;J. Hammond;D. S. Buchanan
中科院分区：
文献类型：
--
作者：
A. Clutter;L. Spicer;M. Woltmann;R. Grimes;J. Hammond;D. S. Buchanan
研究了断奶后快速（F 系，n = 14）或慢速（S 系，n = 14）断奶后日增重猪的后备母猪的生长激素（GH）、IGF-I 和 IGF 结合蛋白（IGFBP）的特性。在禁食期间和重新饲喂期间，从后备母猪（约 55 公斤体重）中重复采集血样。就时间而言，在断食期间，F 和 S 母猪的平均血浆 GH 浓度差异并不显着（7.7 与 6.4 ng/mL；P > .20），并且 F 和 S 猪的 GH 脉冲高度和幅度通常没有差异（P > .25）。总体而言，在断食期间，F 后备母猪的血浆 IGF-I 浓度高于 S 后备母猪（217.3 vs 145.1 ng/mL；P = .40），而在重新饲喂期间，F 和 S 后备母猪的血浆 IGF-I 浓度更高。在重新饲喂期间，F 后备母猪的平均血浆 IGF-I 往往高于 S 后备母猪 (P = .05)。与饲料剥夺期间随时间的变化一致，血浆 IGF-I 平均跨线增加 (P < .01) 以响应重新喂养。跨时间（0 和 48 小时再饲喂）的平均值，F 和 S 后备母猪的 IGFBP-2 活性（34 kDa 处的单线带）没有显着差异 (P = .17)。然而，存在行 x 时间交互的趋势 (P = .13)。（摘要截断为 250 字）
Characteristics of growth hormone (GH), IGF-I, and IGF-binding proteins (IGFBP) were studied in gilts sampled from lines of pigs selected for either fast (line F, n = 14) or slow (line S, n = 14) postweaning ADG. Repeated blood samples were obtained from gilts (approximately 55 kg BW) during a period of feed deprivation and again during refeeding. Averaged across time, the difference in mean plasma GH concentrations of F and S gilts was not significant (7.7 vs 6.4 ng/mL; P > .20) during feed deprivation, and frequently, height, and amplitude of GH pulses did not differ (P > .25) for F and S pigs. Overall, F gilts had greater concentrations of plasma IGF-I than S gilts during feed deprivation (217.3 vs 145.1 ng/mL; P .40) for F and S gilts during the refeeding period. Average plasma IGF-I tended (P = .05) to be greater in F gilts than in S gilts during refeeding. Consistent with changes over time during feed deprivation, plasma IGF-I averaged across line increased (P < .01) in response to refeeding. Averaged across time (0 and 48 h refeeding), activity of IGFBP-2 (singlet band at 34 kDa) did not differ significantly (P = .17) in F and S gilts. However, there was a tendency (P = .13) for a line x time interaction.(ABSTRACT TRUNCATED AT 250 WORDS)