Betel Nut Chewing in Iron Age Vietnam? Detection of Areca catechu Alkaloids in Dental Enamel
Betel Nut Chewing in Iron Age Vietnam? Detection of Areca catechu Alkaloids in Dental Enamel
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DOI：
10.1080/02791072.2016.1264647
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发表时间：
2017-01-01
影响因子：
2.8
通讯作者：
Neukamm, Merja A.
中科院分区：
文献类型：
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作者：
Krais, Simone;Klima, Miriam;Neukamm, Merja A.
槟榔是世界上最常见的精神活性物质。通过考古学证据，如考古遗址中槟榔的出现，史前人类牙齿上典型的整体红棕色染色或与习惯有关的特定文物，人们认为这种传统可以追溯到史前时代。由于这类证据是间接的，因此常常受到怀疑。目前的研究提供了人类历史上最早的咀嚼槟榔的直接分析指标。通过液相色谱-串联质谱法（LC-MS/MS）和液相色谱-高分辨率质谱法（LC-HR-ToF-MS）分析了铁器时代骨骼（越南南部Go O Chua遗址，公元前400-100年）的典型染色牙齿以及槟榔生物碱槟榔碱。（槟榔科）。
The betel quid is one of the most commonly consumed psychoactive substances in the world. By archaeological evidence like the occurrence of areca nuts in archaeological sites, the typical overall reddish-brown staining on prehistoric human teeth or specific artifacts linked with the habit, it is assumed that this tradition reaches back to prehistoric times. Since this kind of evidence is indirect, it is frequently doubted. The present study provides the earliest direct analytical indication of betel nut chewing in human history. A typical stained tooth from an Iron Age skeleton (site Go O Chua in Southern Vietnam, 400-100 BC) was analyzed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) and liquid chromatography-high-resolution mass spectrometry (LC-HR-ToF-MS) and the alkaloid arecoline which is specific for Areca catechu L. (Arecaceae) was detected.