Epidemiology and clinical and pathologic characteristics of cutaneous malignant melanoma in Abruzzo (Italy)
Epidemiology and clinical and pathologic characteristics of cutaneous malignant melanoma in Abruzzo (Italy)
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DOI：
10.1111/j.1365-4632.2009.03974.x
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发表时间：
2009-07-01
影响因子：
3.6
通讯作者：
Tulli, Antonello
中科院分区：
文献类型：
--
作者：
Amerio, Paolo;Manzoli, Lamberto;Tulli, Antonello
背景恶性黑色素瘤的发病率近几十年来在世界范围内呈上升趋势。恶性黑色素瘤在意大利的癌症登记衍生的流行病学数据，只有在一些北方地区的国家.AimTo报告皮肤恶性黑色素瘤在阿布鲁佐，意大利中南部region.MethodsScreening从2002年至2005年的档案的病理部门，区域医院进行了事件的数量和特点。收集每例患者的临床和病理资料。转移性，多发性或复发性黑色素瘤的情况下excluded. ResultsSixhundy和72例原发性黑色素瘤的记录，发病率为14.1每10万居民每年。不同性别（男性41.1%，女性58.9%）和年龄（50-70岁组35%）的患者存在差异，躯干（30.7%）和下肢（25.94%）是最常见的部位。浅表扩散组织型和薄黑色素瘤（< 1.00 mm）更经常记录（44.8%和62%，分别）。ConclusionsDespite偏见存在于本研究中，与数据的性质和来源，我们认为，在本报告中发现的数字是可比的，从其他地中海国家的国际文献中获得的。
BackgroundMalignant melanoma incidence has increased worldwide in recent decades. Cancer registry-derived epidemiologic data on malignant melanoma in Italy are available only in some northern regions of the country.AimTo report the number and characteristics of incident cases of cutaneous malignant melanoma in Abruzzo, a central-southern Italian region.MethodsScreening of the archives of the pathology departments of regional hospitals from 2002 to 2005 was performed. For each patient, clinical and pathologic data were collected. Cases of metastatic, multiple, or relapsing melanoma were excluded.ResultsSix hundred and seventy-two cases of primary melanoma were recorded, with an incidence rate of 14.1 per 100,000 inhabitants per year. Differences related to gender (41.1% males and 58.9% females) and age (35% in the 50-70-year age group) were found. The trunk (30.7%) and lower limbs (25.94%) were the most frequent sites observed. The superficial spreading histiotype and thin melanoma (< 1.00 mm) were more often recorded (44.8% and 62%, respectively).ConclusionsDespite the bias present in this study, linked to the nature and source of the data, we believe that the figures found in this report are comparable with those obtained in the international literature from other Mediterranean countries.