The association between birthweight 4000 g or greater and perinatal outcomes in patients with and without gestational diabetes mellitus
The association between birthweight 4000 g or greater and perinatal outcomes in patients with and without gestational diabetes mellitus
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DOI：
10.1016/j.ajog.2009.02.035
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发表时间：
2009-06-01
影响因子：
9.8
通讯作者：
Caughey, Aaron B.
中科院分区：
文献类型：
--
作者：
Esakoff, Tania F.;Cheng, Yvonne W.;Caughey, Aaron B.
目的：本研究的目的是探讨4000克或更大的出生体重和围产期结局的妇女和没有妊娠期糖尿病（GDM）之间的关联。研究设计：这是一项回顾性队列研究的36,241单胎妊娠分层的诊断GDM，存在或不存在的出生体重4000克或更大。检查的结果包括新生儿高胆红素血症、低血糖、呼吸窘迫综合征（RDS）、肩难产和Erb麻痹。结果：在GDM孕妇中，出生体重≥ 4000 g的新生儿发生低血糖的频率高于出生体重<4000 g的新生儿（5.3% vs 2.6%; P = 0.04），RDS（4.0% vs 1.5%; P = 0.03），肩难产（10.5% vs 1.6%; P
OBJECTIVE: The objective of the study was to examine the association between birthweight of 4000 g or greater and perinatal outcomes in women with and without gestational diabetes mellitus (GDM).STUDY DESIGN: This was a retrospective cohort study of 36,241 singleton pregnancies stratified by the diagnosis of GDM, with presence or absence of birthweight of 4000 g or greater. Outcomes examined included neonatal hyperbilirubinemia, hypoglycemia, respiratory distress syndrome (RDS), shoulder dystocia, and Erb's palsy. chi(2) tests and multivariable logistic regression analyses were used to control for confounders.RESULTS: In women with GDM, neonates with a birthweight of 4000 g or greater, compared with those with a birthweight of less than 4000 g, had higher frequencies of hypoglycemia (5.3% vs 2.6%; P = .04), RDS (4.0% vs 1.5%; P = .03), shoulder dystocia (10.5% vs 1.6%; P