GAUCHER DISEASE - SONOGRAPHIC APPEARANCE OF THE SPLEEN
GAUCHER DISEASE - SONOGRAPHIC APPEARANCE OF THE SPLEEN
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DOI：
10.1148/radiology.160.3.3526400
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发表时间：
1986-09-01
期刊：
影响因子：
19.7
通讯作者：
SHAWKER, TH
中科院分区：
文献类型：
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作者：
HILL, SC;REINIG, JW;SHAWKER, TH
对80例高雪病患者进行了上腹部超声检查。49例未行脾切除术的患者中，47例有脾增大。16例患者脾内有多处病变。大多数患者都有离散的低回声病变，病理上与局灶性同质的高雪氏细胞团相对应。几名患者有类似的病变，呈高回声，由高雪氏细胞和纤维化或梗塞组成。少数患者在正常脾实质中有不规则的高雪氏细胞受累区域。肝脏经常增大，但在其他方面超声表现并不明显。高谢病患者经常因腹痛而接受左上腹超声检查。我们应认识到高谢病在脾中的各种典型表现，而不应将其解释为急性改变。
Ultrasonographic (US) examinations of the upper abdomen were performed in 80 patients with Gaucher disease. Of the 49 patients that had not undergone splenectomy, 47 had splenic enlargment. Sixteen patients had multiple lesions in the spleen. Most patients had discrete hypoechoic lesions that corresponded pathologically to focal homogeneous clusters of Gaucher cells. Several patients had similar lesions that were hyperechoic and were composed of Gaucher cells and fibrosis or infarction. A few patients had a geographic pattern of irregular areas of involvement of Gaucher cells among normal splenic parenchyma. The liver was often enlarged but otherwise sonographically unremarkable. Patients with Gaucher disease often have US examinations of the left upper quadrant for abdominal pain. A variety of us findings in the spleen typical for Gaucher disease should be recognized and not interpreted as acute changes.