Effects of Mahuang Decoction in Different Combinations on Diaphoretic Function in Rats

Effects of Mahuang Decoction in Different Combinations on Diaphoretic Function in Rats
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发表时间:
2005
期刊:
Traditional Chinese Drug Research and Clinical Pharmacology
影响因子:
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通讯作者:
Luo Jia-bo
Luo Jia-bo
中科院分区:
其他
文献类型:
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作者:
Luo Jia-bo

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目的研究麻黄汤不同配伍对大鼠发汗作用的影响。方法观察不同配伍的麻黄汤对大鼠腋窝汗腺发汗作用的影响。方法通过观察大鼠腋窝汗腺空泡的形态变化来评价其发汗作用。结果麻黄与桂枝配伍对大鼠的发汗作用最强,麻黄与桂枝配伍的发汗作用更强。麻黄与桂枝配伍的发汗作用更强。麻黄与桂枝配伍的发汗作用更强。结论麻黄(麻黄)、桂枝(桂枝)、杏仁(杏仁)、甘草(甘草)在麻黄汤中分别起主药、辅药、辅药、传导药的作用,体现了组方方法。
Objective To study the influence of Mahuang Decoction(MD)in different combinations on diaphoretic function in rats.Methods Vacuole incidence of axillary sweat gland was determined by observing the histolomorphological changes of vacuole to evaluate the diaphoretic function.The diaphoretic function was observed in 30 minutes after administration.Results The combination of Mahuang(Herba Ephedrae)and Guizhi(Ramulus Cinnamomi)had the strongest diaphoretic function in all of the different combinations.The diaphoretic function of the combinations including Mahuang(Herba Ephedrae)was stronger than those excluding Mahuang(Herba Ephedrae).The diaphoretic function of Mahuang(Herba Ephedrae)became stronger when used together with Guizhi(Ramulus Cinnamomi),remained the same when used together with Xingren(Semen Armeniacea Amarum),and became weaker when used together with Gancao(Radix Glycyrrhizac).Conclusion Mahuang(Herba Ephedrae),Guizhi(Ramulus Cinnamomi),Xingren(Semen Armeniacea Amarum),and Gancao(Radix Glycyrrhizac)play the roles of principle drug,assistant drug,adjuvant drug and conductantr drug respectively in Mahuang Decoction,which embodying the method of composing a prescription.