Patterns of spread of squamous cell carcinoma within the mandible
Patterns of spread of squamous cell carcinoma within the mandible
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下颌骨内鳞状细胞癌的扩散模式
DOI：
10.1002/hed.2880110513
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
Alexandra Garven
中科院分区：
文献类型：
--
作者：
MD A. D. McGregor;PhD D. G. MacDonald;Simone McGregor;Mrs. Ingrid McGregor;Alexandra Garven
在43个未照射的下颌骨（33个无牙和10个部分有牙）和16个照射的下颌骨中的鳞状细胞癌的扩散模式进行了研究。确定了两种扩散模式：（1）与下牙槽神经相关的扩散，以及（2）在松质骨小梁之间的间隙中扩散。尽管无牙颌的神经相关扩散明显比部分齿状未辐照下颌骨更频繁，但所有未辐照下颌骨和辐照下颌骨之间的发生率差异不显著。辐照和未辐照下颌骨松质骨的扩散模式差异不大。肿瘤在骨髓内扩散，深入到骨外软组织肿瘤范围以外的完整皮质，是罕见的。
The patterns of spread of squamous cell carcinoma within the mandible were investigated in 43 nonirradiated (33 edentulous and 10 partially dentate) and 16 irradiated mandibles. Two modes of spread were identified: (1) spread in relation to the inferior alveolar nerve, and (2) spread in spaces between cancellous bony trabeculae. Although nerve‐related spread was significantly more frequent in the edentulous than in the partially dentate nonirradiated mandible, the difference in incidence between all nonirradiated mandibles and irradiated mandibles was not significant. The patterns of spread in cancellous bone in irradiated and nonirradiated mandibles differed little. Spread of tumor within the medulla, deep to an intact cortex beyond the extent of extraosseous soft tissue tumor, was seen infrequently.