RNAstructure: Web servers for RNA secondary structure prediction and analysis.
RNAstructure: Web servers for RNA secondary structure prediction and analysis.
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RNAstructure:用于RNA二级结构预测和分析的Web服务器。
DOI:
10.1093/nar/gkt290
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发表时间:
2013-07
影响因子:
14.9
通讯作者:
Mathews DH
中科院分区:
文献类型:
--
作者:
Bellaousov S;Reuter JS;Seetin MG;Mathews DH
RNAstructure is a software package for RNA secondary structure prediction and analysis. This contribution describes a new set of web servers to provide its functionality. The web server offers RNA secondary structure prediction, including free energy minimization, maximum expected accuracy structure prediction and pseudoknot prediction. Bimolecular secondary structure prediction is also provided. Additionally, the server can predict secondary structures conserved in either two homologs or more than two homologs. Folding free energy changes can be predicted for a given RNA structure using nearest neighbor rules. Secondary structures can be compared using circular plots or the scoring methods, sensitivity and positive predictive value. Additionally, structure drawings can be rendered as SVG, postscript, jpeg or pdf. The web server is freely available for public use at: http://rna.urmc.rochester.edu/RNAstructureWeb.
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