Dual energy computed tomography in tophaceous gout
Dual energy computed tomography in tophaceous gout
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DOI：
10.1136/ard.2008.099713
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发表时间：
2009-10-01
影响因子：
27.4
通讯作者：
Nicolaou, S.
中科院分区：
文献类型：
--
作者：
Choi, H. K.;Al-Arfaj, A. M.;Nicolaou, S.
目的：评估双能 CT (DECT) 扫描在评估痛风石性痛风患者尿酸盐沉积方面的潜在效用，并获得外周关节痛风石体积的计算机量化结果。方法：纳入 20 名连续的痛风石患者和 10 名患有其他关节炎疾病的对照患者。使用肾结石颜色编码方案进行 DECT 扫描，该方案专门评估材料的化学成分（即尿酸盐呈红色，钙呈蓝色）。使用 DECT 自动体积评估来测量所有外周关节区域尿酸盐沉积物的体积。结果：所有 20 名痛风患者在 DECT 扫描中均显示出红色编码的尿酸盐沉积物，而 10 名对照者均未显示尿酸盐沉积物。 DECT 扫描显示 20 名患者总共 440 个尿酸盐沉积区域，而体检显示 111 个尿酸盐沉积区域（平均每名患者分别 22 个和 6 个，p
Objective: To evaluate the potential utility of a dual energy CT (DECT) scan in assessing urate deposits among patients with tophaceous gout, and obtain computerised quantification of tophus volume in peripheral joints.Methods: 20 consecutive patients with tophaceous gout and 10 control patients with other arthritic conditions were included. DECT scans were performed using a renal stone colour-coding protocol that specifically assessed the chemical composition of the material (ie, urate coloured in red, calcium coloured in blue). An automated volumetric assessment of DECT was used to measure the volume of urate deposits in all peripheral joint areas.Results: All 20 patients with gout showed red colour-coded urate deposits on their DECT scans, whereas none of 10 controls showed urate deposits. DECT scans revealed a total of 440 areas of urate deposition in 20 patients, whereas physical examination showed 111 areas of urate deposition (mean 22 vs 6 per patient, respectively, p