A single-chip signal processing and telemetry engine for an implantable 96-channel neural data acquisition system
A single-chip signal processing and telemetry engine for an implantable 96-channel neural data acquisition system
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DOI：
10.1088/1741-2560/4/3/016
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发表时间：
2007-09-01
影响因子：
4
通讯作者：
Wolf, Patrick D.
中科院分区：
文献类型：
--
作者：
Rizk, Michael;Obeid, Iyad;Wolf, Patrick D.
完全植入式神经数据采集系统是临床可行的皮层脑机接口的关键组成部分。我们提出了一个单芯片设备，服务于这样一个系统的处理需求的设计和实现。我们的设备处理96个通道的多单元神经数据，并执行双向无线通信所需的所有数字处理。该实现利用单个可编程逻辑器件，该器件负责在96个神经数据通道上执行数据简化，向收发器提供双向遥测接口，并执行命令解释和系统监督。该设备将以31.25 kHz采样的神经数据作为输入，并输出包含要由收发器发送的信息的行编码串行比特流。数据可以以以下四种模式之一输出：（1）从单个通道流式传输未压缩数据，（2）从96个通道的任何子集提取尖峰波形，（3）每个通道的1 ms bincounts或（4）从单个通道流式传输数据沿着提取的尖峰。该设备每秒可输出高达2000个提取的尖峰，适合脑机接口应用。该器械提供完全植入式系统所需的所有数字处理组件。
A fully implantable neural data acquisition system is a key component of a clinically viable cortical brain-machine interface. We present the design and implementation of a single-chip device that serves the processing needs of such a system. Our device processes 96 channels of multi-unit neural data and performs all digital processing necessary for bidirectional wireless communication. The implementation utilizes a single programmable logic device that is responsible for performing data reduction on the 96 channels of neural data, providing a bidirectional telemetry interface to a transceiver and performing command interpretation and system supervision. The device takes as input neural data sampled at 31.25 kHz and outputs a line-encoded serial bitstream containing the information to be transmitted by the transceiver. Data can be output in one of the following four modes: (1) streaming uncompressed data from a single channel, (2) extracted spike waveforms from any subset of the 96 channels, (3) 1 ms bincounts for each channel or (4) streaming data along with extracted spikes from a single channel. The device can output up to 2000 extracted spikes per second with latencies suitable for a brain-machine interface application. This device provides all of the digital processing components required by a fully implantable system.