BREAST-CARCINOMA AT THE EXTREMES OF AGE - A COMPARISON OF PATIENTS YOUNGER THAN 35 YEARS AND OLDER THAN 75 YEARS
BREAST-CARCINOMA AT THE EXTREMES OF AGE - A COMPARISON OF PATIENTS YOUNGER THAN 35 YEARS AND OLDER THAN 75 YEARS
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DOI：
10.1002/jso.2930280204
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发表时间：
1985-01-01
影响因子：
2.5
通讯作者：
KINNE, DW
中科院分区：
文献类型：
--
作者：
ROSEN, PP;LESSER, ML;KINNE, DW
预后评估患者乳腺癌的极端年龄分布的疾病。研究对象包括166名年龄在35岁以下的女性和169名年龄在75岁以上的女性。复发率和生存率分析显示，两组之间整体或按淋巴结状态分层均无显著差异。与正常年龄匹配的人群相比，患乳腺癌的老年妇女的预期寿命明显缩短。髓质癌多见于年轻女性；胶质癌和浸润性小叶癌在老年妇女中发病率相对较高。双侧癌在两个年龄组中发现的频率几乎相同。然而，老年妇女更有可能以前接受过对侧癌的治疗；年轻女性倾向于发展为非同步的继发性癌。
The prognosis was assessed of patients with breast carcinoma at the extremes of the age distribution of the disease. The groups examined were 166 women who were 35 yr or less and 169 at least 75 yr old. Analysis of recurrence and survival showed no significant difference between the groups as a whole or when they were stratified by nodal status. Life expectancy of elderly women with breast carcinoma was significantly reduced when compared with a normal age-matched population. Medullary carcinoma was more frequent in young women; a relatively higher proportion of colloid and invasive lobular carcinoma occurred in elderly women. Bilateral carcinoma was found with nearly equal frequency in both age groups. However, elderly women were more likely to have been treated previously for contralateral carcinoma; young women tended to develop asynchronous, subsequent carcinoma.