Both relative insulin resistance and defective islet β-cell processing of proinsulin are responsible for transient hyperglycemia in extremely preterm infants
Both relative insulin resistance and defective islet β-cell processing of proinsulin are responsible for transient hyperglycemia in extremely preterm infants
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DOI：
10.1542/peds.113.3.537
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发表时间：
2004-03-01
期刊：
影响因子：
8
通讯作者：
Voyer, M
中科院分区：
文献类型：
--
作者：
Mitanchez-Mokhtari, D;Lahlou, N;Voyer, M
Objective.许多极早产儿在出生后的第一周内在持续葡萄糖输注期间发生高血糖症。本研究的目的是确定胰岛素分泌缺陷或胰岛素抵抗是否是极早产儿短暂性高血糖的主要因素。在适合胎龄早产儿中进行了一项前瞻性比较研究
Objective. Many extremely preterm infants develop hyperglycemia in the first week of life during continuous glucose infusion. The objective of this study was to determine whether defective insulin secretion or resistance to insulin was the primary factor involved in transient hyperglycemia of extremely preterm infants.Methods. A prospective comparative study was conducted in appropriate-for-gestational-age preterm infants