Thermal holographic patterns for ultrasound hyperthermia

Thermal holographic patterns for ultrasound hyperthermia
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DOI:
10.1063/5.0081565
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发表时间:
2022-02-21
影响因子:
4
通讯作者:
Camarena, Francisco
Camarena, Francisco
中科院分区:
物理与天体物理2区
文献类型:
--
作者:
Andres, Diana;Vappou, Jonathan;Camarena, Francisco

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全息图可以塑造波前以产生任意的声学图像。在这项工作中,我们实验演示如何声全息图可以产生控制的热模式在吸收介质中的超声频率。磁共振成像(MRI)兼容的全息超声透镜是通过时间反转方法设计的,并使用3D打印制造。几个热全息图案进行了测量,使用MRI测温和热成像相机在明胶牛奶幻影和在离体肝组织。结果表明,声全息图可以在任意区域进行空间控制加热。使用低成本和MRI兼容的全息换能器来增加温度可能对于许多生物医学应用(诸如超声热疗)具有极大的兴趣,其中需要控制特定的热模式。由AIP Publishing独家授权出版。
Holograms can shape wavefronts to produce arbitrary acoustic images. In this work, we experimentally demonstrate how acoustic holograms can produce controlled thermal patterns in absorbing media at ultrasonic frequencies. Magnetic resonance imaging (MRI)-compatible holographic ultrasound lenses were designed by time-reversal methods and manufactured using 3D-printing. Several thermal holographic patterns were measured using MRI thermometry and a thermographic camera in gelatin-milk phantoms and in an ex vivo liver tissue. The results show that acoustic holograms enable spatially controlled heating in arbitrary regions. Increasing the temperature using low-cost and MRI-compatible holographic transducers might be of great interest for many biomedical applications, such as ultrasound hyperthermia, where the control of specific thermal patterns is needed. Published under an exclusive license by AIP Publishing.