The role of androgens in microvascular endothelial dysfunction in polycystic ovary syndrome: does size matter?
The role of androgens in microvascular endothelial dysfunction in polycystic ovary syndrome: does size matter?
复制标题
雄激素在多囊卵巢综合征微血管内皮功能障碍中的作用：大小重要吗？
DOI：
10.1113/jp277961
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发表时间：
2019
期刊：
影响因子：
--
通讯作者：
DuBose,LyndseyE
中科院分区：
文献类型：
--
作者：
Moreau,KerrieL;DuBose,LyndseyE
本文分析了雄激素在多囊卵巢综合征（PCOS）微血管内皮功能障碍中的作用。讨论的主题包括减少内皮素B受体介导的微血管内皮功能障碍在PCOS女性中的作用及其与高雄激素血症、雄激素受体介导的内皮型一氧化氮合酶（eNOS）激活和NO释放的相关性，以及需要更好地了解PCOS女性预防的病理生理学。
The article analyzes role of androgens in microvascular endothelial dysfunction in polycystic ovary syndrome (PCOS). Topics discussed include the role of reduced endothelin B receptor-mediated microvascular endothelial dysfunction in women with PCOS and their association with hyperandrogenism, androgen receptor-mediated activation of endothelial nitric oxide synthase (eNOS) and NO release, and need to have better understanding of the pathophysiology for preventing in women with PCOS.