Examination of differential anxiety sensitivities in panic disorder:: A test of anxiety sensitivity subdomains predicting fearful responding to a 35% CO2 challenge
Examination of differential anxiety sensitivities in panic disorder:: A test of anxiety sensitivity subdomains predicting fearful responding to a 35% CO2 challenge
复制标题
DOI：
10.1023/a:1018754522981
复制
发表时间：
1999-02-01
影响因子：
2.8
通讯作者：
Schmidt, NB
中科院分区：
文献类型：
--
作者：
Schmidt, NB
惊恐障碍的认知概念化表明，惊恐是由与自主觉醒相关的威胁性信念产生和维持的。本研究通过评估特定焦虑敏感度域的差异预测来测试恐慌的焦虑敏感度模型的判别效度。身体感觉问卷的因素分析表明，四个嵌套的焦虑敏感性因素评估心肺，分离，麻木和胃肠道感觉的恐惧。由每个因素评估的症状具有与35%CO2吸入期间通常产生的感觉的不同水平的对应性（即，心脏病恐惧/高对应性、分离恐惧/中度对应性、麻木恐惧/中度对应性、胃肠道恐惧/低对应性）。假设对高对应性感觉的焦虑敏感性与对中等和低对应性感觉的焦虑敏感性相比，可以预测对35%CO2挑战的更大恐惧反应。符合DSM-IV惊恐障碍标准的五十六人完成了一次肺活量35%CO2挑战。与预测一致，心脏病恐惧是唯一的指标，预测挑衅引起的焦虑和症状。这些发现表明，特定的焦虑敏感性可以提供一个更强大的解释模型，预测惊恐障碍的情绪反应。
Cognitive conceptualizations of panic disorder suggest that panic is produced and maintained by threatening beliefs associated with autonomic arousal. The present study tested the discriminant validity of the anxiety sensitivity model of panic by assessing the differential predictions of particular anxiety sensitivity domains. A factor analysis of the Body Sensations Questionnaire indicated four nested anxiety sensitivity factors assessing fears of cardiopulmonary, dissociation, numbness, and gastrointestinal sensations. The symptoms assessed by each factor possess varying levels of correspondence to the sensations typically produced during a 35% CO2 inhalation (i.e., Cardiopulmonary Fears/High Correspondence, Dissociation Fears/Moderate Correspondence, Numbness Fears/Moderate Correspondence, Gastrointestinal Fears/Low Correspondence). It was hypothesized that anxiety sensitivity to the high-correspondence sensations, compared to anxiety sensitivity to moderate- and low-correspondence sensations would predict greater fearful responding to a 35% CO2 challenge. Fifty-six participants meeting DSM-IV criteria for panic disorder completed a single vital capacity 35% CO2 challenge. Consistent with prediction, Cardiopulmonary Fears was the only index that predicted provocation-induced anxiety and symptoms. These findings suggest that specific anxiety sensitivities can provide a more powerful explanatory model for predicting emotional responding in panic disorder.