Unusual complication of aluminum phosphide poisoning: Development of hemolysis and methemoglobinemia and its successful treatment.

Unusual complication of aluminum phosphide poisoning: Development of hemolysis and methemoglobinemia and its successful treatment.
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DOI:
10.4103/0972-5229.83021
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发表时间:
2011-04
期刊:
Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine
影响因子:
--
通讯作者:
Shadnia S
Shadnia S
中科院分区:
其他
文献类型:
--
作者:
Soltaninejad K;Nelson LS;Khodakarim N;Dadvar Z;Shadnia S

文献摘要

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高铁血红蛋白血症和溶血是罕见的发现后,磷化氢中毒。本文报告一例磷化铝中毒并发高铁血红蛋白血症和溶血,经抢救成功。一名28岁的男性患者出现后,故意摄入的AlP片剂。在该病例中,血尿、溶血和高铁血红蛋白血症为显著事件。通过CO-血氧测定法检测到高铁血红蛋白水平为46%。患者接受抗坏血酸和亚甲蓝治疗,并接受支持性治疗。入院两周后,患者出院。溶血和高铁血红蛋白血症可使磷化氢中毒的病程复杂化。
Methemoglobinemia and hemolysis are rare findings following phosphine poisoning. In this paper, a case of aluminum phosphide (AlP) poisoning complicated by methemoglobinemia and hemolysis with a successful treatment is reported. A 28-year-old male patient presented following intentional ingestion of an AlP tablet. In this case, hematuria, hemolysis and methemoglobinemia were significant events. A methemoglobin level of 46% was detected by CO-oximetry. The patient was treated with ascorbic acid and methylene blue and he also received supportive care. Two weeks after admission, the patient was discharged from the hospital. Hemolysis and methemoglobinemia may complicate the course of phosphine poisoning.