The eqpidemilogy of skin cancer in Queensland: the influence of phenotype and environment.
The eqpidemilogy of skin cancer in Queensland: the influence of phenotype and environment.
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DOI：
10.1038/bjc.1970.27
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发表时间：
1970-06
影响因子：
8.8
通讯作者：
Searle, J H
中科院分区：
文献类型：
--
作者：
Silverstone, H;Searle, J H
根据昆士兰3个相距遥远的地区的长期居民收集的数据，对皮肤癌和日光角化病的病因中的一些因素的影响进行了多元分析。考虑的因素包括年龄、性别、对晒伤的易感性、肤色、眼睛颜色、血统、职业、衣着习惯和居住地。事实证明，对于两性、疾病和所有年龄段的人来说，“对晒伤的易感性”是最有力的单一判别因素。总体而言，遗传因素作为一个群体似乎比环境因素提供了更多关于易感性的信息。“占领”的相对重要性仍然存在一些疑问。在远离海岸的热带地区，这似乎是相当重要的。在沿海地区，它的影响力似乎被削弱了，大概是因为运动和娱乐习惯等因素。
On the basis of data gathered from long term residents of 3 widely separated regions of Queensland a multivariate analysis has been made to determine the influence of a number of factors in the aetiology of skin cancer and solar keratosis. Factors considered were age, sex, susceptibility to sunburn, complexion, eye colour, ancestry, occupation, clothing habits and residential district. For both sexes, both diseases and all age groups the factor “susceptibility to sunburn” proved to be the most powerful single discriminant. On the whole it appeared that the genetically based factors as a group provided more information on susceptibility than the environmental factors. The relative importance of “occupation” remains in some doubt. In the tropical area away from the coast it appears to be of considerable importance. In coastal areas its influence appears to be blunted, presumably by factors such as sports and recreation habits.