Serum soluble death receptor 5 concentration in patients with chronic hepatitis B is associated with liver damage and viral antigen level
Serum soluble death receptor 5 concentration in patients with chronic hepatitis B is associated with liver damage and viral antigen level
复制标题
慢性乙型肝炎患者血清可溶性死亡受体5浓度与肝损伤及病毒抗原水平相关
DOI：
10.1016/j.clinbiochem.2012.04.007
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发表时间：
2012-07-01
影响因子：
2.8
通讯作者：
Liang, Xiaohong
中科院分区：
文献类型：
--
作者：
Du, Juan;Wang, Lei;Liang, Xiaohong
目的：目的：检测B型肝炎患者血清可溶性死亡受体5（sDR 5）水平，方法：采用ELISA法检测60例HBV感染者和30例健康志愿者血清sDR 5水平。结论：血清sDR5水平降低与肝损害程度增高有关，并抑制了HBV抗原的表达。(C)2012年加拿大临床化学家协会。爱思唯尔公司出版All rights reserved.
Objectives: To measure the levels of serum soluble death receptor 5 (sDR5) in patients with hepatitis B.Design and methods: sDR5 concentration in 60 HBV infected patients and 30 healthy volunteers were measured by ELISA.Results: sDR5 concentration in the HBV infected patients was decreased and correlated with serum ALT. Tbil level, albumin/globulin ratio and HBV antigen level.Conclusions: Decreased serum sDR5 is associated with high level of liver damage and inhibited HBV antigen expression. (C) 2012 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.