Short term effects of airborne pollen concentrations on asthma epidemic

Short term effects of airborne pollen concentrations on asthma epidemic
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DOI:
10.1136/thorax.58.8.708
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发表时间:
2003-08-01
期刊:
影响因子:
10
通讯作者:
Aránguez, E
Aránguez, E
中科院分区:
医学1区
文献类型:
--
作者:
Tobías, A;Galán, I;Aránguez, E

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背景资料:很少有研究使用时间序列来调查哮喘发作和空气过敏原水平之间的关系,每天based.Methods:这项研究,根据时间序列分析调整气象因素和空气污染变量,评估短期影响不同类型的过敏性花粉对哮喘医院急诊在大都市地区的马德里(西班牙)为1995年8月。在统计学上,禾本科花粉(滞后3天)和Plantogo花粉(滞后2天),在第99至95个季度之间的范围内增加了17.1%(95%置信区间(0)3.2至32.8)和15.9%(95% CI 6.5至26.2)。还观察到一个积极的关联荨麻科(滞后1天)增加8.4%(95%CI 2.8至14.4)。结论:花粉水平和哮喘相关的紧急情况之间存在关联,独立于空气污染物的影响。观察到的显着的关系,禾本科和车前花粉表明,他们的含义在哮喘的流行分布期间,符合他们突然释放到环境中。
Background: Few studies have used time series to investigate the relationship between asthma attacks and aeroallergen levels on a daily basis.Methods: This study, based on time series analysis adjusting for meteorological factors and air pollution variables, assessed the short term effects of different types of allergenic pollen on asthma hospital emergencies in the metropolitan area of Madrid (Spain) for the period 1995-8.Results: Statistically significant associations were found for Poaceae pollen (lag of 3 days) and Plantogo pollen (lag of 2 days), representing an increase in the range between the 99th and 95th percentiles of 17.1% (95% confidence interval (0) 3.2 to 32.8) and 15.9% (95% Cl 6.5 to 26.2) for Poaceae and Plantogo, respectively. A positive association was also observed for Urticaceae (lag of 1 day) with an 8.4% increase (95% Cl 2.8 to 14.4).Conclusions: There is an association between pollen levels and asthma related emergencies, independent of the effect of air pollutants. The marked relationship observed for Poaceae and Plantago pollens suggests their implication in the epidemic distribution of asthma during the period coinciding with their abrupt release into the environment.