Lack of utility of specific immunoglobulin G antibody avidity for serodiagnosis of reactivated toxoplasmosis in immunocompromised patients
Lack of utility of specific immunoglobulin G antibody avidity for serodiagnosis of reactivated toxoplasmosis in immunocompromised patients
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DOI：
10.1128/cdli.7.4.703-705.2000
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发表时间：
2000-07-01
期刊：
影响因子：
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通讯作者：
Derouin, F
中科院分区：
文献类型：
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作者：
Mechain, B;Garin, YJF;Derouin, F
在出现脑或脑外弓形虫病和/或血清学再激活的免疫应答患者中测量弓形虫特异性免疫球蛋白G血清抗体的活力。由于40例弓形虫病患者中的39例和28例血清学再激活患者中的27例的贪食度仍然很高且稳定，我们得出结论，该试验不能帮助诊断这些患者的弓形虫病。
The avidities of Toxoplasma-specific immunoglobulin G serum antibodies were measured in immunocom-promised patients presenting with cerebral or extracerebral toxoplasmosis and/or serological reactivation. Since avidity remained high and stable in 39 of 40 patients with toxoplasmosis and 27 of 28 patients with serological reactivation, we conclude that this test cannot help diagnose toxoplasmosis in these patients.