Targeted enzyme-responsive drug carriers: Studies on the delivery of a combination of drugs
Targeted enzyme-responsive drug carriers: Studies on the delivery of a combination of drugs
复制标题
DOI：
10.1002/anie.200353204
复制
发表时间：
2004-03-19
影响因子：
16.6
通讯作者：
Shin, I
中科院分区：
文献类型：
--
作者：
Lee, MR;Baek, KH;Shin, I
Double whammy: Effective and selective killing of E. coli cells containing a specific enzyme was achieved by using targeted enzyme-responsive drug carriers (see picture) that release free drugs in a stringently controlled manner. The carrier lowered the effective concentration of drug needed to kill the bacteria. The system could also be modified to deliver a combination of two drugs.
