RF inhomogeneity compensation in structural brain imaging

RF inhomogeneity compensation in structural brain imaging
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DOI:
10.1002/mrm.10050
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发表时间:
2002-02-01
影响因子:
3.3
通讯作者:
Turner, R
Turner, R
中科院分区:
医学3区
文献类型:
--
作者:
Deichmann, R;Good, CD;Turner, R

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三维T-1加权磁化制备的快速梯度回波(MP-RAGE)序列在内环具有中心相位编码(PE),可提供高空间分辨率和高组织对比度的结构脑图像。这种序列类型的缺点是对射频(RF)线圈的不均匀性敏感,这可能导致某些外围区域的图像对比度较差。提出了一种特殊的激励脉冲,它在头/脚和前后方向上都补偿了这些影响。该脉冲的持续时间仅为1.3毫秒,因此与MP-RAGE成像所需的短重复时间(TRs)兼容。实验表明,在数据后处理过程中,用补偿脉冲采集的图像可以在不使用亮度校正算法的情况下进行分割。《医学评论》47:398-402,2002。(C)2002年Wiley-Liss,Inc.
Three-dimensional T-1-weighted magnetization-prepared rapid gradient-echo (MP-RAGE) sequences with centric phase encoding (PE) in the inner loop provide structural brain images with a high spatial resolution and high tissue contrast. A disadvantage of this sequence type is the susceptibility to inhomogeneities of the radiofrequency (RF) coil, which may result in poor image contrast in some peripheral regions. A special excitation pulse is presented which compensates for these effects in both the head/foot and anterior/posterior directions. This pulse has a duration of only 1.3 ms and is thus compatible with the short repetition times (TRs) required for MP-RAGE imaging. It is shown experimentally that images acquired with the compensation pulse may be segmented without using intensity correction algorithms during data postprocessing. Magn Reson Med 47:398-402, 2002. (C) 2002 Wiley-Liss, Inc.