Direct observation of single RNA polymerase processing through a single endogenous gene in a living yeast cell.
Direct observation of single RNA polymerase processing through a single endogenous gene in a living yeast cell.
复制标题
通过活酵母细胞中的单个内源基因直接观察单个 RNA 聚合酶的加工过程。
作者：
B. Treutlein;J. Michaelis
活细胞成像技术的快速发展使我们能够直接观察来自内源性酵母基因的单个新生mRNA分子的转录。荧光标记mRNA的一种新的定量波动分析揭示了转录起始动力学和延伸和终止动力学。
Rapid advances in live-cell imaging have now enabled direct observation of the transcription of single nascent mRNA molecules from an endogenous yeast gene. A novel quantitative fluctuation analysis of fluorescently labeled mRNA revealed the kinetics of transcription initiation and the dynamics of elongation and termination.
影响因子：
5.6
作者：
Herbert KM;Zhou J;Mooney RA;Porta AL;Landick R;Block SM
通讯作者：
Block SM
基因表达的单分子视图。
影响因子：
19
作者：
Larson, Daniel R.;Singer, Robert H.;Zenklusen, Daniel
通讯作者：
Zenklusen, Daniel