Porphyromonas gingivalis may multiply and advance within stratified human junctional epithelium in vitro.
Porphyromonas gingivalis may multiply and advance within stratified human junctional epithelium in vitro.
复制标题
牙龈卟啉单胞菌可以在体外的人分层交界上皮内繁殖和前进。
DOI：
10.1111/j.1600-0765.1994.tb01237.x
复制
发表时间：
1994
影响因子：
3.5
通讯作者：
Nannmark,U
中科院分区：
文献类型：
--
作者：
Papapanou,PN;Sandros,J;Lindberg,K;Duncan,MJ;Niederman,R;Nannmark,U
牙周病原体牙龈卟啉单胞菌与口腔上皮细胞之间的体外相互作用近年来一直是不同实验室研究的主题。作者最近研究了牙龈假单胞菌粘附和侵袭体外口袋上皮的潜力。从患者牙周手术中获得的培养袋上皮组织产生了分层上皮。该上皮随后被实验室和临床的牙龈假单胞菌感染。在用抗生素混合物杀死细胞外细菌并将裂解的上皮细胞镀在培养基上后，对这些菌株的侵袭潜力进行了量化。
In vitro interactions between the periodontal pathogen Porphyromonas gingivalis and oral epithelial cells have lately been the subject of study in different laboratories. Authors recently examined the potential of P. gingivalis to adhere to and invade in vitro pocket epithelium. Cultured pocket epithelial tissue, obtained from patients in conjunction with periodontal surgery, generated a stratified epithelium. This epithelium was subsequently infected by laboratory and clinical strains of P. gingivalis. The invasive potential of these strains was quantitated after killing extracellular bacteria with an antibiotic mixture and plating lysed epithelial cells on culture media.