Organometallic anticancer complexes of lapachol: metal centre-dependent formation of reactive oxygen species and correlation with cytotoxicity
Organometallic anticancer complexes of lapachol: metal centre-dependent formation of reactive oxygen species and correlation with cytotoxicity
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DOI：
10.1039/c3cc40432c
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发表时间：
2013-01-01
影响因子：
4.9
通讯作者：
Hartinger, Christian G.
中科院分区：
文献类型：
--
作者：
Kandioller, Wolfgang;Balsano, Evelyn;Hartinger, Christian G.
金属有机配合物Ru-II、Os-II和Rh-III通过氧化应激的作用方式诱导低MUM范围内的人肿瘤细胞系的凋亡，特别是在Ru化合物的情况下。
Organometallic Ru-II, Os-II and Rh-III complexes of lapachol induce apoptosis in human tumour cell lines in the low mu M range by a mode of action involving oxidative stress, especially in the case of the ruthenium compound.