Kinetics of release of norepinephrine by tyramine.
Kinetics of release of norepinephrine by tyramine.
复制标题
酪胺释放去甲肾上腺素的动力学。
DOI：
10.1016/0024-3205(65)90069-x
复制
发表时间：
1965
期刊：
影响因子：
6.1
通讯作者：
B. Brodie
中科院分区：
文献类型：
--
作者：
N. Neff;T. Tozer;W. Hammer;B. Brodie
为了解释各种药物的作用，本实验室配制了l86ß ie70xoa ~ n~ n~ eaer。缓解voi。4, xo。它是一个理论模型，与现有的事实相一致，整合了NE的形成、储存、释放和代谢的单元（8,9,10,11）。该模型是一个开放的双室系统，由一个随时可用的动态平衡的自由NE室和一个更大的颗粒中络合的NE室组成。两个池中NE的关系用台地作用动力学描述如下：
To interpret the action of various drugs this laboratory has formulated l86ß ie7o xoa~ n~ n~ E aEr. EASE voi. 4, xo. i9 a theoretical model, compatible with available facto, of the unit that inter grates the formation, storage, release and metabolism of NE (8, 9, 10, 11). This model is an open two-compartment system consisting of a readily available compartment of free NE in dynamic equilibrium with a larger compartment of NE complexed in granules. The relationship between NE in the two pools is described by mesa action kinetics as follows: