Paralytic toxins in Taiwanese starfish Astropecten scoparius
Paralytic toxins in Taiwanese starfish Astropecten scoparius
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DOI：
10.1016/s0041-0101(97)00161-x
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发表时间：
1998-05-01
期刊：
影响因子：
2.8
通讯作者：
Hwang, DF
中科院分区：
文献类型：
--
作者：
Lin, SJ;Tsai, YH;Hwang, DF
1995年12月至1996年11月，在台湾屏东海域每10个海星样本中检测到麻痹性毒性。总样本的最高毒性和平均毒性（以河豚毒素（TTX）表示）分别为5，938和1，679小鼠单位（MU）。内脏和其他部位的月平均毒性最高值分别为354和247 MU/g。经YM-2膜超滤和Bio-Gel P-2柱层析，毒素得到部分纯化。HPLC和GC-MS分析表明，海星毒素主要由河豚毒素（88%）组成，沿着少量的膝螺毒素2-3和石房蛤毒素（12%）。(C)1998爱思唯尔科技有限公司版权所有。
Paralytic toxicity was seasonally detected in every 10 specimens of the starfish Astropecten scoparius from Pingtung in Taiwan from December 1995 to November 1996. The highest toxicity and the average toxicity of total specimens, expressed as tetrodotoxin (TTX), were 5,938 and 1,679 mouse unit (MU), respectively. The highest value of monthly average toxicity in viscera and other parts were 354 and 247 MU/g, respectively. The toxin was partially purified by YM-2 membrane ultrafiltration and Bio-Gel P-2 column chromatography. HPLC and GC-MS analyses showed that the starfish toxin was mainly composed of tetrodotoxin (88%), along with minor gonyautoxin 2-3 and saxitoxin (12%). (C) 1998 Elsevier Science Ltd. All rights reserved.