The race between host and sea lice in the Chilean salmon farming: a genomic approach
The race between host and sea lice in the Chilean salmon farming: a genomic approach
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DOI：
10.1111/raq.12334
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发表时间：
2019-05-01
影响因子：
10.4
通讯作者：
Valenzuela-Munoz, Valentina
中科院分区：
文献类型：
--
作者：
Gallardo-Escarate, Cristian;Arriagada, Gabriel;Valenzuela-Munoz, Valentina
海虱是一组体外寄生桡足类动物，在世界范围内的鲑鱼养殖业中对鱼类健康产生负面影响。由于它们的生物学特性，包括对化疗剂具有不同敏感性的几个发育阶段及其复杂的宿主-寄生虫相互作用，海虱的控制是可持续水产养殖的主要障碍之一。需要采取跨学科的方法，以避免在鱼类生产周期中商业使用的抗寄生虫药对环境的影响，以及虱子种群中日益出现的耐药性。在此，基于基因组分析的控制方法将允许开发新的工具，例如疫苗、免疫调节剂、饲料中掩蔽化合物和非药物疗法。这篇综述强调了宿主和海虱之间的种族基因组知识，重点是萨尔莫和Oncorhynchus kisutch作为宿主鱼类和Caligus rogercresseyi作为影响智利鲑鱼产业的主要威胁。
Sea lice are a group of ectoparasite copepods negatively affecting fish health in the salmon farming industry worldwide. Due to their biology, including several stages of development with different sensitivities to chemotherapeutants and their complex host-parasite interactions, the control of sea lice represents one of the major obstacles for sustainable aquaculture. Interdisciplinary approaches are required to avoid the environmental impacts of antiparasites commercially used during the fish production cycle and the increasing emergence of drug resistance in lice populations. Herein, control methods based on genomic analyses will allow for the development of novel tools such as vaccines, immune-modulators, in-feed masking compounds and non-pharmacological therapies. This review highlights the genomic knowledge on the race between hosts and sea lice, with emphasis on Salmo salar and Oncorhynchus kisutch as host fish species and Caligus rogercresseyi as the main threat affecting the Chilean salmon industry.