Iodine deficiency disorders in Bangladesh, 2004-05: ten years of iodized salt intervention brings remarkable achievement in lowering goitre and iodine deficiency among children and women.
Iodine deficiency disorders in Bangladesh, 2004-05: ten years of iodized salt intervention brings remarkable achievement in lowering goitre and iodine deficiency among children and women.
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孟加拉国的碘缺乏病，2004-05：十年的碘盐干预在降低儿童和妇女的甲状腺肿和碘缺乏方面取得了显著成就。
DOI：
10.6133/apjcn.2008.17.4.13
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发表时间：
2008
影响因子：
1.3
通讯作者：
Islam Phd
中科院分区：
文献类型：
--
作者：
Harun K;Yusuf Phd;M. Mustafizur;Rahman Msc;Fatima Parveen;Chowdhury Mphil;M. Mohiduzzaman Msc;Cadi Parvin;Banu Msc;M. Arif;Sattar Msc;M. Nurul;Islam Phd
进行了一项调查，以监测孟加拉国6-12岁儿童和15-44岁妇女的缺碘性疾病现状，以甲状腺肿患病率和尿碘排泄量为衡量标准。该调查于2004年9月至2005年3月进行，采用分层多阶段整群抽样设计，以提供具有全国代表性的数据，并进行了自我加权的城乡分类。共对7233名儿童和6408名妇女进行了甲状腺肿检查，并对4848份尿样（2447份来自儿童，2401份来自妇女）进行了碘分析。此外，还对5321份家庭食盐样品进行了碘分析。儿童的甲状腺肿大率为6.2%，而1993年为49.9%，妇女的甲状腺肿大率为11.7%，而1993年为55.6%。碘缺乏症（尿碘排泄量<100微克/升）的患病率在儿童中为33.8%，在妇女中为38.6%（1993年分别为71.0%和70.2%）。城市碘营养状况明显好于农村。碘缺乏与使用适当碘盐（≥ 15 ppm）的家庭覆盖率之间存在明显的负相关关系。调查结果显示，自10年前开始实施全民食盐加碘方案以来，孟加拉国在降低儿童和妇女甲状腺肿大率和碘缺乏症方面取得了值得称道的进展。然而，三分之一以上的儿童和妇女仍然存在生理性碘缺乏症，这表明所有利益攸关方需要加倍努力，实现食盐普遍加碘。
A survey was conducted to monitor the current status of iodine deficiency disorders in children aged 6-12 years and women aged 15-44 years in Bangladesh as measured by goitre prevalence and urinary iodine excretion. Conducted between September 2004 and March 2005, the survey followed a stratified multistage cluster sampling design to provide nationally representative data, with self-weighted rural-urban disaggregation. A total of 7233 children and 6408 women were examined for goitre and 4848 urine samples (2447 from children and 2401 from women) were analyzed for iodine. In addition, 5321 household salt samples were analyzed for iodine. In children, the total goitre rate (TGR) was 6.2%, compared to 49.9% in 1993 and the TGR among women was 11.7%, while in 1993 it was 55.6%. Prevalence of iodine deficiency (Urinary Iodine Excretion <100 microg/L) was 33.8% in children and 38.6% in women (compared to 71.0% and 70.2%, respectively in 1993). Iodine nutrition status in urban areas was considerably better than in rural areas. There was a clear inverse relationship between iodine deficiency and the coverage of households using adequately iodized salt (> or =15 ppm). The findings of the survey revealed that Bangladesh has achieved a commendable progress in reducing goitre rates and iodine deficiency among children and women ever since the universal salt iodization programme was instituted 10 years ago. However, physiological iodine deficiency still persists among more than one-third of children and women, which points to the need for all stakeholders to redouble their efforts in achieving universal salt iodization.