Maximum intensity projection (MIP) imaging using slice-stacking MRI
Maximum intensity projection (MIP) imaging using slice-stacking MRI
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DOI：
10.1118/1.3503850
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发表时间：
2010-11-01
期刊：
影响因子：
3.8
通讯作者：
Cai, Jing
中科院分区：
文献类型：
--
作者：
Adamson, Justus;Chang, Zheng;Cai, Jing
目的：评价一种新的层叠磁共振成像(SS-MRI)技术获取最大密度投影(MIP)图像的可行性。在每个轴位切片上，在一个呼吸周期内重复扫描。四个物体(小、中、大三角形和一个圆柱体)随着患者的呼吸轨迹移动，使用层叠MRI和4D-CT重复成像六次。对MIP(SS-MRI)和MIP(4D-CT)进行重建。在6次扫描中对每个对象的内部靶体积(ITV)进行分割，并与MIP(SS-MRI)和MIP(4D-CT)进行比较。采用层叠MRI、4D-CT和矢状位电影MRI对正中三角进行不同的运动模式成像。重建相应的MIP图像，进行体积/面积测量，并比较不同成像方法之间的差异。三名健康志愿者接受了层叠MRI和矢状面电影MRI扫描。在MIP(SS-MRI)和MIP(电影-MRI)中为每个受试者选择和勾画感兴趣区(ROI)。结果：MIP(SS-MRI)和MIP(4D-CT)的平均ITV差异无统计学意义(均P>；0.05)。对于具有多种运动方式的中三角，MIP(SS-MRI)和MIP(4D-CT)的ITVS测量结果有很好的一致性(p=0.46，相关系数=0.91)，平均相差1.4%+/-4.4%。MIP(SS-MRI)和MIP(Cine-MRI)的面积测量也有很好的一致性(p=0.47，相关系数=0.97)，平均相差0.2%+/-2.9%。在健康志愿者研究中，MIP(SS-MRI)和MIP(Cine-MRI)所选ROI面积的平均差异为-2.5%+/-2.5%。结论：这些初步结果表明，层叠MRI技术与4D-CT/Cine-MRI在体积/面积测量上具有良好的一致性，表明该技术用于MIP成像是可行的。(C)2010年美国医学物理学家协会。[DOI：10.1118/1.3503850]
Purpose: To evaluate the feasibility of acquiring maximum intensity projection (MIP) images using a novel slice-stacking MRI (SS-MRI) technique.Methods: The proposed technique employed a steady state acquisition sequence to image multiple axial slices. At each axial slice, the scan is repeated throughout one respiratory cycle. Four objects (small, medium, and large triangles, and a cylinder) moving with a patient breathing trajectory were imaged repeatedly for six times using the slice-stacking MRI and 4D-CT. MIP(SS-MRI) and MIP(4D-CT) were reconstructed. The internal target volume (ITV) was segmented for each object on the six scans and compared between MIP(SS-MRI) and MIP(4D-CT). The medium triangle was also imaged with various motion patterns using slice-stacking MRI, 4D-CT, and sagittal cine-MRI. The corresponding MIP images were reconstructed and volume/area measurements were performed and compared between different imaging methods. Three healthy volunteers underwent the slice-stacking MRI and sagittal cine-MRI scans. A region of interest (ROI) was selected and contoured for each subject in both MIP(SS-MRI) and MIP(cine-MRI). The area of the selected ROI was computed and compared.Results: Volume comparison between MIP(SS-MRI) and MIP(4D-CT) showed statistically insignificant (p > 0.05 in all cases) difference in the mean ITVs for all four objects. For the study of the medium triangle with multiple motion patterns, there was a good agreement in the measured ITVs between MIP(SS-MRI) and MIP(4D-CT) (p=0.46, correlation coefficient=0.91), with a mean difference of 1.4% +/- 4.4%. The area measurements between MIP(SS-MRI) and MIP(cine-MRI) also showed good agreement (p=0.47, correlation coefficient=0.97), with a mean difference of 0.2% +/- 2.9%. For the healthy volunteer study, the average difference in the area of selected ROI was -2.5% +/- 2.5% between MIP(SS-MRI) and MIP(cine-MRI).Conclusions: These preliminary results showed good agreement in volume/area measurements between the slice-stacking MRI technique and 4D-CT/cine-MRI, indicating that it is feasible to use this technique for MIP imaging. (C) 2010 American Association of Physicists in Medicine. [DOI: 10.1118/1.3503850]