Structure and function of the parasitophorous vacuole in Eimeria species
Structure and function of the parasitophorous vacuole in Eimeria species
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DOI：
10.1016/s0020-7519(98)00079-4
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发表时间：
1998-07-01
影响因子：
4
通讯作者：
Werner-Meier, R
中科院分区：
文献类型：
--
作者：
Entzeroth, R;Mattig, FR;Werner-Meier, R
艾美耳球虫的细胞内生命周期阶段位于寄主细胞内的一个膜结合的寄生虫液泡中。侵染过程和寄生液泡的形成是由顶端复合体中特有的细胞器介导的。在入侵期间，寄生虫操纵寄生液泡膜，并在发育周期的后期作为分子筛发挥作用，允许寄生虫和宿主细胞之间的代谢物交换。与形成包囊的球虫不同的是，在艾美耳球虫生命周期的后期，几乎没有证据表明寄生虫-空泡膜转化。与人类病原体疟原虫和弓形虫相比，艾美耳球虫属动物病原体的寄生液泡和寄生液泡膜知之甚少。(C)1998年澳大利亚寄生虫学学会。爱思唯尔科学有限公司出版。
The intracellular life-cycle stages of Eimeria are located in the host cell within a membrane-bound parasitophorous vacuole. The invasion process and the formation of the parasitophorous vacuole are mediated by characteristic organelles within the apical complex. During invasion, the parasitophorous-vacuole membrane is manipulated by the parasite and functions later in the development cycle as a molecular sieve, allowing the exchange of metabolites between parasite and host cell. Unlike the cyst-forming coccidia, there is little evidence of parasitophorous-vacuole membrane transformation in the later stages of the lifecycle of Eimeria species. Compared with the human pathogens Plasmodium and Toxoplasma, rather little is known about the parasitophorous vacuole and parasitophorous-vacuole membrane of animal pathogens of the genus Eimeria. (C) 1998 Australian Society for Parasitology. Published by Elsevier Science Ltd.