Intravenous Contrast Medium Administration and Scan Timing at CT: Considerations and Approaches
Intravenous Contrast Medium Administration and Scan Timing at CT: Considerations and Approaches
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DOI：
10.1148/radiol.10090908
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发表时间：
2010-07-01
期刊：
影响因子：
19.7
通讯作者：
Bae, Kyongtae T.
中科院分区：
文献类型：
--
作者：
Bae, Kyongtae T.
在过去的几十年中，计算机断层扫描（CT）技术的持续进步为改善CT图像质量和临床实践以及发现新的临床CT成像应用提供了持续的机会。然而，新的CT技术在临床放射学实践中引入了新的挑战。其中一个挑战是静脉注射造影剂和扫描时间。在这篇文章中，造影剂的药代动力学和患者，造影剂，CT扫描与对比增强和扫描时间的因素进行了介绍和讨论。对造影剂和生理学临床研究的已发表数据进行审查和解释。计算机模拟数据进行了分析，以提供与对比度增强和扫描定时相关的各种因素的深入分析。在基本原理和因素分析的基础上，提出了优化普通临床CT应用的对比增强所需的临床考虑和方案设计的修改。(C)RSNA，2010年
The continuing advances in computed tomographic (CT) technology in the past decades have provided ongoing opportunities to improve CT image quality and clinical practice and discover new clinical CT imaging applications. New CT technology, however, has introduced new challenges in clinical radiology practice. One of the challenges is with intravenous contrast medium administration and scan timing. In this article, contrast medium pharmacokinetics and patient, contrast medium, and CT scanning factors associated with contrast enhancement and scan timing are presented and discussed. Published data from clinical studies of contrast medium and physiology are reviewed and interpreted. Computer simulation data are analyzed to provide an in-depth analysis of various factors associated with contrast enhancement and scan timing. On the basis of basic principles and analysis of the factors, clinical considerations and modifications to protocol design that are necessary to optimize contrast enhancement for common clinical CT applications are proposed. (C) RSNA, 2010