Carcinogenesis by avian sarcoma viruses.

Carcinogenesis by avian sarcoma viruses.
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DOI:
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发表时间:
1968-09
期刊:
影响因子:
11.2
通讯作者:
H. Temin
H. Temin
中科院分区:
医学1区
文献类型:
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作者:
H. Temin

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Habel博士对病毒致癌生物学的当前工作进行了出色的总结。鉴于他自己实验室的工作,他强调了DNA肿瘤病毒的大小。以我们实验室对含RNA的禽肉瘤病毒的研究为基础,正如Habel博士所指出的,这种病毒比DNA肿瘤病毒具有更简单和更直接的作用,我想重申Habel博士的一些观点,并将锡永扩展到支持以下致癌机制的假设:
Dr. Habel has presented an excellent summary of current work on the biology of viral carcinogenesis. As is appropriate in view of the work from his own laboratory, he has empha sized the DNA tumor viruses. Using as a base the work from our laboratory with the RNA-containing avian sarcoma viruses, which, as Dr. Habel has indicated, have a simpler and more direct action than do the DNA tumor viruses, I should like to reiterate some of Dr. Habel's points and to extend the discus sion to support the following hypothesis of the mechanism of carcinogenesis:Agenetic