Altering body position affects intraocular pressure and visual function.
Altering body position affects intraocular pressure and visual function.
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DOI：
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发表时间：
1988-10
影响因子：
4.4
通讯作者：
B. J. Linder;Gory L. Trick;Mirchel L. Wolf
中科院分区：
文献类型：
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作者：
B. J. Linder;Gory L. Trick;Mirchel L. Wolf
改变身体位置可以改变眼压（IOP）。本报告描述了两项评估眼压变化以及与全身低头倾斜相关的视网膜和视觉皮层神经功能（通过模式反转视网膜电图和视觉诱发电位测量）变化的实验。每个实验有 10 名受试者，视觉正常，眼压小于 19。在第一个实验中，通过在 +90 度（直立）和 -90 度（倒置）之间以不连续的步长改变倾斜角度来诱导眼压升高。在每个位置测量眼压并记录显着升高（高达基线的 3 倍）。这些升高保持 1 分钟，在此期间同时测量视网膜和皮质生物电势。在第二个实验中，保持6度低头倾斜2小时，在此期间重复测量眼压和生物电势。我们的研究结果证实了身体姿势对眼压的影响，同时也揭示了低头倾斜会导致视网膜和皮质水平的神经生理功能显着降低。当保持 6 度低头倾斜 20 分钟时，神经效应最大化。
Intraocular pressure (IOP) can be altered by changing body position. This report describes two experiments evaluating variations in IOP, as well as neural functioning of the retina and visual cortex (as measured by pattern-reversal electroretinogram and visual evoked potential), associated with whole-body, head-down tilt. The subjects, ten per experiment, were visually normal with IOP less than 19. In the first experiment, IOP elevations were induced by varying the angle of tilt in discrete steps between +90 degrees (upright) and -90 degrees (inverted). In each position IOP was measured and significant elevations (up to 3x baseline) were noted. These elevations were maintained for 1 min during which simultaneous retinal and cortical biopotentials were measured. In the second experiment, 6 degrees head-down tilt was maintained for 2 hr during which time the IOP and both biopotentials were measured repeatedly. Our findings confirm the effect of body position of IOP, while also revealing that head-down tilt produces significant reductions in neurophysiological function at both the retinal and cortical levels. The neural effect is maximized when 6 degrees head-down tilt is maintained for 20 min.