Seeing the unexpected: how sex differences in stress responses may provide a new perspective on the manifestation of psychiatric disorders.
Seeing the unexpected: how sex differences in stress responses may provide a new perspective on the manifestation of psychiatric disorders.
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DOI：
10.1007/s11920-002-0072-z
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发表时间：
2002-12-01
影响因子：
6.7
通讯作者：
Corwin, Elizabeth J
中科院分区：
文献类型：
--
作者：
Klein, Laura Cousino;Corwin, Elizabeth J
在这份报告中，作者提出，对压力的生物行为反应中潜在的性别差异可能是一些基于性别的精神障碍患病率差异的原因。作者从应激生理学的讨论开始，回顾了一种关于应激反应中的性别差异(即“照顾和成为朋友”反应)的新理论，该理论可能为最近在某些精神疾病的表现中考虑性别差异提供了一个框架。然后，作者讨论了严重的抑郁症和注意缺陷多动障碍，作为压力反应的性别差异如何影响精神障碍的行为症状的例子，精神障碍的行为症状在一种性别比另一种性别更容易被诊断出来。作者最后简要讨论了这一新观点对治疗方法的影响，并鼓励进一步探讨基于性别的差异在一些精神疾病的行为表现中的重要性。
In this report, the authors propose that underlying sex differences in the biobehavioral response to stress may contribute to the variance in prevalence of some psychiatric disorders based on sex. The authors begin with a discussion of stress physiology and review a new theory on sex differences in stress responses (ie, the "tend-and-befriend" response), which may provide a recent framework for considering sex differences in the manifestation of some psychiatric illnesses. The authors then move to a discussion of major depression and attention deficit hyperactivity disorder as examples of how sex differences in stress responses may influence the behavioral symptoms of psychiatric disorders that are more often diagnosed in one sex compared with another. The authors conclude with a brief discussion of the implications of this new perspective on treatment approaches and encourage further inquiry into the importance of sex-based differences in the behavioral manifestation of some psychiatric illnesses.