Novel zinc/tungsten carbide nanocomposite as bioabsorbable implant
Novel zinc/tungsten carbide nanocomposite as bioabsorbable implant
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DOI：
10.1016/j.matlet.2019.127282
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发表时间：
2020-03-15
影响因子：
3
通讯作者：
Li, Xiaochun
中科院分区：
文献类型：
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作者：
Guan, Zeyi;Linsley, Chase S.;Li, Xiaochun
缺乏具有足够机械强度的生物可吸收材料，适用于在恢复组织完整性的同时提供临时支撑的植入应用，特别是在儿科应用中。生物可吸收金属由于其强度、延展性和体内生物相容性的结合而成为一种有吸引力的选择。锌作为一种生物可吸收金属显示出巨大的应用前景，但纯锌的力学性能较差，限制了其作为植入材料的应用。本研究以碳化锌-碳化钨纳米复合材料作为生物可吸收金属植入物的新型材料进行研究。采用超声波辅助粉末压制技术制备了锌-碳化钨纳米复合材料。这项研究包括材料的微观结构、显微硬度和降解性的表征。结果表明，纳米碳化钨提高了锌的力学性能，并保持了纯锌的良好腐蚀速率。这些结果鼓励进一步研究生物医学应用的锌-碳化钨纳米复合材料，最终目标是为许多临床应用创造安全和有效的生物可吸收金属植入物。(C)2020爱思唯尔B.V.保留所有权利。
There is a lack of bioabsorbable materials with adequate mechanical strength suitable for implant applications that provide temporary support while tissue integrity is restored, especially for pediatric applications. Bioabsorbable metals have emerged as an attractive choice due to their combination of strength, ductility, and biocompatibility in vivo. Zinc has shown great promise as a bioabsorbable metal, but the weak mechanical properties of pure zinc limit its application as an implant material. This study investigates zinc-tungsten carbide (Zn-WC) nanocomposite as a novel material for bioabsorbable metallic implants. Ultrasound-assisted powder compaction was used to fabricate Zn-WC nanocomposites. This study includes the material characterization of microstructure, microhardness, and degradability. Results showed that tungsten carbide nanoparticles enhanced the mechanical properties of Zn, and maintained the favorable corrosion rate of pure Zn. These results encourage further investigation of Zn-WC nanocomposites for biomedical applications with the ultimate goal of creating safe and efficacious bioabsorbable metallic implants for many clinical applications. (C) 2020 Elsevier B.V. All rights reserved.