Risk of house staff tuberculin skin test conversion in an area with a high incidence of tuberculosis
Risk of house staff tuberculin skin test conversion in an area with a high incidence of tuberculosis
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DOI：
10.1086/514963
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发表时间：
1998-10-01
影响因子：
11.8
通讯作者：
Shulman, JA
中科院分区：
文献类型：
--
作者：
Blumberg, HM;Sotir, M;Shulman, JA
我们前瞻性地评估了1992年7月至1997年6月埃默里大学附属医院培训计划中格雷迪纪念医院（亚特兰大）结核病扩大感染控制措施实施后的医务人员结核菌素皮肤试验（TST）转换率，该医院每年治疗约200例结核病患者。在5年内，2，144名员工中有52名（2.4%）发生了记录在案的TST转换。在接下来的4.5年中，前6个月的转换率从5.98/100人-年降至1.09/100人-年（P <0.001）。多变量分析显示，TST转换的风险因素包括从外国医学院毕业和成为医学系的内部员工;种族或民族，性别和年龄不是风险因素。在过去的4.5年中，美国医学院研究生院工作人员（n = 1，928）的TST转换率为0.72/100人-年工作，并且在医学系和其他部门的院工作人员之间的转换率没有显着差异。总之，在全面实施扩大的结核病感染控制措施后，TST血清转换率显著下降，
We prospectively evaluated rates of tuberculin skin test (TST) conversion from July 1992 to June 1997 among house staff in the Emery University Affiliated Hospitals Training Program following implementation of expanded infection control measures for tuberculosis at Grady Memorial Hospital (Atlanta), which cares for similar to 200 patients with tuberculosis per year. Over 5 years, documented TST conversions occurred for 52 (2.4%) of 2,144 house staff. Conversion rates decreased after the first 6 months from 5.98 to 1.09 per 100 person-years worked over the next 4.5 years (P < .001), Multivariate analysis revealed that risk factors for TST conversion included graduation from a foreign medical school and being part of the house staff in the Department of Medicine; race or ethnicity, gender, and age were not risk factors. Over the last 4.5 years, the TST conversion rate among U,S, medical school graduate house staff(n = 1,928) was 0.72 per 100 person-years worked, and there was no significant difference in conversion rates between house staff in the Department of Medicine and house staff in other departments. In summary, TST seroconversion rates decreased significantly following full implementation of expanded infection control measures for tuberculosis and were low (